The solution for organizing and analysing your microbes.

Phylogenetic Trees

OpenGenomeBrowser can generate and display phylogenetic trees using three distinct algorithms:

trees demo

How to get there

In the genome table, select multiple genomes (using Shift and Ctrl) and open the context menu using right click. Then, click on Show phylogenetic trees.

Advanced usage

Through the settings sidebar, it is possible to apply custom colors to the genomes in the tree.

Copy on the newick string to copy the dendrogram, for example to use it in other tools (e.g. or itol)

Additional downloads:


GenDisCal, preset approxANI

The distance matrix is based on whole genome nucleotide similarity calculated using GenDisCal (Goussarov et al., Bioinformatics, 2020) with the approxANI preset. This preset is documented as follows:

approxANI is a minhash-based approximation of Average Nucleotide Identity (ANI). This method is similar to the one used by the Mash software (Ondov et al., Gen. biol., 2016) The ambiguity region for species is [0.04-0.06]

Thus, the GenDisCal similarities should produce values that strongly correlate with original ANI, but can be computed much faster.